You might be surprised at how unoriginal some box-art is.
Found a neat website the other day surfing the Internets. It tracks certain resemblances between video game characters and celebrities. Take a look at a few and judge for yourself.
This first one isn't a video game character, but a video game star nonetheless: no other than famous heroic Mario and Zelda developer Shigeru Miyamoto:

Hmm... an Asian Austin Powers? Not convinced?
How about this one: the resemblance is hard not to notice here between Big Boss, from the Metal Gear Solid Series, and...

...suave aging Hollywood legend Sean Connery. Really -- was Big Boss based on Mr. Connery perhaps?
And on the subject of Metal Gear, how about this image of Solid Snake, featured on the original NES game's box art:

Whoa! Really! I think we have found some similarities here! Perhaps the source of inspiration for the box art, perhaps? Hmm..
Similar situation with something more recent:

What's going on here? Seems like there is some big time 'inspiration' going on, that's for sure.
For more celebrity lookalikes and real-world resemblances of game characters, check out J.R Antrim's Videogame Lookalike site.
