Arkane Studios has said Dishonored can be completed without killing a single soul.
Even though players will take the role of a protagonist who's an assassin, co-creative directors Harvey Smith and Raphael Colantonio stated that you won't have to kill anyone in order to complete Dishonored.
"Yes, you can complete the game without killing anyone. (It was a goal of ours.) And the world reflects that to some extent."
Smith added that players will be able to complete the title via several "weird" ways.
"As players we're always trying to do things we didn't do last time. Our programmers were all trying to do crazy weird variants this week. 'The Falling Angel playthrough,' where you only kill by using drop-assassination."
When asked if by not killing anyone would cause players to miss out on potential powers, Colantonio replied:
"Well, by definition, yes. You'll miss the assassination anims and a couple of powers like Devouring Swarm and Shadow Kill. But playing nonlethally (and with total stealth, on a higher difficulty) often forces very tense cool moments...sublime tension as my friend Randy Smith (from Thief) likes to say. So it's a trade-off."
Dishonored is due for a release on October 9 2012 in North America and three days later in Europe.