Because The Infected have been hit badly with the Ophiocordyceps unilateralis virus, they no longer appear to be solely human. Instead of having their normal face, they are warped to a form that varies between the creatures. However, they still appear to be human, just with the destroyed face.
The Infected act as wolves when they swarm. They are often seen in packs, and they always go in snarling and have been seen travelling on all fours. However, they are able to stand, as seen when one attacks Joel. They now have a taste for blood, similar to that of a bat, and try to bite into humans.
Despite their warped appearance, they still share some of the weaknesses of a normal human. In a trailer, Ellie stabs one of the monsters, causing it to recoil and jump off of Joel, showing that they still can be harmed in that way.
So it seems to be a pretty crazy infection that spreads through blood or saliva contact through your stream possibly like Zombies? That is just my first guess but it could have spread another way. I like their design though and I think they will be quite creepy and challenging if they are as fast as they were on the trailer during gameplay. I wander if they will take the prominent enemy role or if they will take a smaller spot to the hunters we saw in the gameplay trailer, only time can tell.
Thread Recap (last 10 posts from newest to oldest)
Feb 6, 13 at 2:31pm
I don't think there would be bosses, at least nothing major. Perhaps one at the end, but more of a harder part in the game, rather than some boss creature.
Feb 6, 13 at 12:47pm
I don't think there will be any bosses. If any they'd be human, and would be similar to any Uncharted bosses (no major mutation or anything, more down to earth type of boss).
Feb 6, 13 at 11:06am
It sounds awesome. I wonder if there will be a boss or a few bosses.
Feb 6, 13 at 11:04am
Yogurt Yeah, the third type is supposed to be in between runners and clickers, I think.
Spoiler:Interview with Neil Druckman about recent gameplay trailer
Feb 5, 13 at 5:31am
There's three types of Infected; runners, clickers and a secretive one. I wonder what the secretive one will be like and if they will showcase it before the game is released, even just for a very short while.
Jan 6, 13 at 9:10am
The design is absolutely frekin' amazing, and if they're anything like the Ancestors from Uncharted 1, they're definitely going to give me a hard time whilst playing the game. I do wonder if the Infected are going to be limited to humans? Will we see some infected animals?
Sep 28, 12 at 8:13am
The infected "clickers" i assume would act like the flood in halo, in relation to other enemy types, i.e. dumb and go straight for you so normal ways of play "point a gun at the enemy and they run" wont work. I'm reading up on it here if you wanna have a look guys: http://gamewise.co/games/45504/The-Last-of-Us
Sep 27, 12 at 2:50pm
I think they're going to be a LOT worst. After all, it is half a game dedicated to these guys.