King's Grail Room Strategy

I don't actually remember this room as much as other parts of the game actually. I remember always being scared of it because i played Easy quite a few times first (wasn't a great gamer back then) so it was quite 'daunting'.

I think i used the shotgun as well, tried to get as many of the helmets off before throwing a flash. Getting all 3 in one flash would be ideal but if i was struggling i'd get rid of 2 of them so i'd only have 1 enemy left. That was pretty much my strategy, run around like a maniac and every now and then turn and blast the shottie.

My original strategy consisted mostly of fleeing in a panic-stricken blur.

In Normal mode, let Leon get hit by one of the QTE knights in the corridor. The game will make the knights a lot easier as a result.

I used to minimize use of flash grenades, limiting myself to just two and getting three knights with each, but here's what I do now.

Get the free Broken Butterfly. Upgrade its firepower as much as possible. Use its original six shots then upgrade its capacity to eight. Save those for the knights.

Collect 4-6 blue flash grenades and 2-4 green hand grenades.

As Spontex said, leave Ashley outside.

Also, set a continue point just before starting the battle, to avoid having to endure the QTE knight events again.

Position Leon to pick up the Grail facing the middle knight, the one opposite the entrance. Equip the bolt action rifle (or semi-automatic rifle) and pre-aim for the middle knight.

Get the grail and interrupt the cutscene to give Leon as much of a position advantage as possible.

Headshot the middle knight. If this fails I restart from the continue point.

Pause for a second so that the other two knights go into their attacks. Back up and drop a green hand grenade on the three knights. It's tricky to get all three of them without causing Leon to flinch, but if you do the knights will fall to their knees. That gives time to set up the Broken Butterfly.

Headshot one of the intact knights with the Broken Butterfly. The game can be pretty glitchy about recognizing a headshot here. About 50% of the time even a perfect shot, with aiming dot, will not register.

Equip a blue hand grenade. Wait for a second (maybe two) for the second plagas to fully sprout, then flash the two plagas out of existence.

This will cause the third knight to kneel, if I remember correctly. Headshot with Broken Butterfly and use another blue flash grenade. Grab the death drops and position Leon as before.

Repeat the process. Under ideal circumstances there will still be six shots in the BB, average four shots remaining. Worst case there are still two shots, enough to get the final two knights after headshotting the middle one with the rifle.

Emergency weapon is the TMP. Leon can upgrade its capacity to 150 with the Merchant just before this fight. If things go badly (and sometimes they will), a single remaining knight can be taken down with the TMP upgraded as far as possible to that point. Get a little distance, and zap the knight's helmet with a medium burst. It will headshake and stagger a bit. Repeat a few times. When the helmet bursts open the TMP will quickly take down the plagas that sprouts.

The extra grenades can also be used when things go wrong. Both blue and green grenades will cause the knights to stumble to their knees, giving Leon the precious time necessary to set up for the kill.