Alisa is 100% virtually impossible to defeat due to her unstoppable flying attacks in Scenario Campaign, Alisa is the last boss and cannot be defeated and consequentially, Lars dies as a result. That's the real ending. This unfaithful tragedy could've been avoided...

I have also confirmed 100% that this game contains no Platinum Trophy due to the programming infection of Alisa. No one can defeat her. Furthermore, Lars' health is a maximum of 126. You can't raise it any further. Alisa cannot be defeated. I am very right. I am the best at analyzing. I know damn well how STUPID NAMCO *bleep*IN' BANDAI GAMES REALLY IS!!!!!!!!!!!! BASTARDS!!!

i beat her... so I think its possible

Cant you not play the computer at a single Vs match?

Agreed, Alisa is insane, I haven't beaten her as of yet. She pushes you into the corner, and continues a relentless assault (especially since she's equipped with the ice element).

However, she doesn't seem impossible, I've been pretty close with Bryan.

My usual strategy is to take out one of the henchmen as soon as possible, then leave the health items for when you need it. Keep away from Alisa while doing so, as she will only taunt (and recover health while doing it!) with the occasional rocket punch here and there. The second henchman should drop while you're taking out Alisa, as they seem to get in the way more than actually attack you.

As for Alisa herself, you should pick up one of the yellow energy drinks behind your starting position to get the upper hand. This way you can combo at her without her breaking your combo by unleashing her chainsaws at you. Once it runs out, try your hardest to get out of her reach and grab the second, by now you should have here at a third of her health.

I've gotten her down to the smallest amount of health before getting combo'd to death by those chainsaws, so I'm pretty sure I'll get there eventually.

Oh man i just beat her ... I found combing moves that freeze and set you opponent on fire help. Also once you get rid of those two goons that help her, use the yellow drink bottles and just combo her ass lol. Then run and kick her continuously. Hope it helps.

100% possible as I have the platnum for this game.