- Four game modes: Puzzle, Endless, Vs. and the brand new Shooting Mode.
- Supports up to 8 players simultaneously in Vs. mode.
- Master 500 levels in 5 Puzzle Mode areas
- 10 different playable characters including franchise favorites Bub and Bob plus many new additions.
- Use both the Wii Remote, Nunchuk or Classic controller to hit bubbles coming from all directions in Shooting Mode.
- New "Hyper" option speeds up gameplay while the "Slip" option lets you connect your fired bubbles to similar colors even if your aim is off.
- Gallery Mode lets players access in-game artwork.
This game is also known as Puzzle Bobble Bash! in Japan.