Complete each achievement to get the allotted gamerscore. The numbers between the () is the points given for each achievement.
| Achievement | How to unlock |
| To Aedirn! (5) | Complete Chapter 1. |
| Alea lacta Est (10) | Complete Chapter 2. |
| Once Ain't Enough (15) | Complete Chapter 3. |
| Apprentice (10) | Use alchemy to brew five potions or oils. |
| Master Alchemist (10) | Acquire the Mutant ability. |
| The Butcher of Blaviken (30) | Kill 500 foes. |
| Miser (10) | Collect 10000 orens. |
| Focus (30) | Perform three successful ripostes in a row. |
| Craftsman (10) | Hire a craftsman to create an item. |
| Pest Control (20) | Finish all quests involing the destruction of monster nests. |
| Torn Asunder! (15) | Kill more than one opponent using a single exploding bomb. |
| Gambler (15) | Win an arm wrestling match, a dice poker game and a fist fight. |
| Gladiator (15) | Defeat all opponents in the Kaedweni arena. |
| Madman (100) | Finish the game while playing at the Dark difficulty level. |
| Journeyman (10) | Achieve character level 10. |
| Guru (50) | Achieve character level 35. |
| Master of Magic (10) | Acquire the Sense of Magic ability. |
| Mutant! (30) | Enhance abilities using mutagens at least five times. |
| Last Man Standing (15) | Survive your 30th fight in the Arena |
| Perfectionist (15) | Kill 10 foes in a row without losing any Vitality. |
| Poker! (30) | Roll five-of-a-kind at dice poker. |
| Tried-and-True (10) | Survive your 5th fight in the Arena |
| The Fugitive (5) | Complete the Prologue. |
| Ricochet (10) | Kill a foe by deflecting his own arrow at him. |
| Swordmaster (10) | Acquire the Combat Acumen ability. |
| To Be Continued... (50) | Finish the game at any difficulty level. |
| Threesome (15) | Kill three foes at once by performing a group finisher. |
| Secret Achievements | - |
| Avenger (30) | Finish the game by killing Letho. |
| Backbone (20) | Craft a suit of armor from elements of the kayran's carapace. |
| Being Witcher George (20) | Kill the dragon. |
| Fat Man (15) | Kill the draug. |
| Eagle Eye (10) | Hit Count Etcheverry using the ballista. |
| Heartbreaker (10) | Seduce Ves. |
| Kingmaker (15) | Help Roche rescue Anais from the Kaedweni camp. |
| Dragonheart (20) | Spare or save Saskia. |
| Librarian (30) | Find all additional information about the insane asylum's history. |
| Necromancer (50) | Relive all of Auckes's memories in Dethmold's vision. |
| Old Friends (30) | Finish the game by sparing Letho. |
| Sensitive Guy (10) | Save Síle from dying in the unstable portal. |
| Intimidator (15) | Intimidate someone. |
| Man of the Shadows (15) | Successfully sneak through Loredo's garden and find the component of the kayran trap. |
| Black Ops (20) | Sneak through the lower camp without raising the alarm. |
| Spellbreaker (15) | Help Iorveth find the dagger needed to free Saskia from the spell that holds her. |
| Reasons of State (15) | Stop Roche from killing Henselt. |
| Kayranslayer (10) | Kill the kayran. |
| Artful Dodger (30) | Cut off a tentacle using the kayran trap. |
| Tourist (10) | Tour the camp with Zyvik. |
| Friend of Trolls (15) | Spare all trolls in the game. |
| Trollslayer (30) | Kill all the trolls in the game. |
| Witch Hunter (10) | Leave Síle to die in the unstable portal. |