Complete each achievement to get the allotted gamerscore. The numbers between the () is the points given for each achievement.
| Achievement | How to unlock |
|---|
| The Berserker (10) | Complete Phase 2: The Doll that Bled. |
| Be Garbage of Cesspool (20) | Complete Phase 4: The Meat Factory. |
| Experiment 765 (30) | Complete Phase 6: Beast with a Human Heart. |
| Shattered Narcissus (40) | Complete Phase 8: Reflections in Blood. |
| Pyre for the Damned (50) | Complete Phase 10: The Wicker Bride. |
| Bride of the Corrupted (100) | Complete the game on any difficulty. |
| I Walk with Death (110) | Complete the game on "Savage" difficulty (or harder). |
| Dreams of the Dead (120) | Complete the game on "Brutal" Difficulty. |
| Death Came Ripping (5) | Kill an enemy with a Splatter Slash. |
| Razor of Hell (5) | Get 100 kills with Splatter Slash. |
| Must Kill (5) | Kill an enemy with Splatter Smash. |
| Downpour of Blood (5) | Get 100 kills with Splatter Smash. |
| Flesh Re-animation! (5) | Regenerate with Splatter Siphon. |
| One Who Slays (5) | Get 300 kills in Berserker Mode. |
| Heavy Frikkin' Metal! (5) | Get 50 kills with non-fleshy weapons. |
| Triumph of Iron (15) | Get 500 kills with non-fleshy weapons. |
| See you at the Party (5) | Kill an enemy with an enemy's arm. |
| None More Dead (10) | Get 150 kills with enemy arms. |
| Tongue in Cheek (5) | Kill an enemy with an enemy's head. |
| Head on Arrival (10) | Get 50 kills with enemy heads. |
| You Got Red on You (5) | Splat an enemy on a wall with a weapon. |
| Blood and Lightning (5) | Splat 100 enemies on a wall with a weapon. |
| The Blackest of Sundays (10) | Splat 200 enemies on a wall with a weapon. |
| The Business of Killing (5) | Perform a Splatterkill. |
| South of Hell (5) | Perform 75 Splatterkills. |
| Vigorous Vengeance (10) | Perform 150 Splatterkills. |
| Morbid Dismemberment (5) | Kill an enemy with your own dismembered arm. |
| Brain Dead (5) | Tackle an enemy and pummel it 20 times. |
| Bad Taste (5) | Impale an enemy on a spike. |
| Army of Dead Evil (5) | Kill 6 enemies within one second. |
| Headlong into Monsters (5) | Kill 6 enemies in one ram attack. |
| POW! (5) | Launch an enemy straight up with "No Head Room". |
| Barrels of Blood (5) | Get 2000 or more BLOOD Points in one chain of attacks. |
| Audiophile (5) | Listen to all of Dr. West's gramophone records. |
| Boreworm Massacre (10) | Stomp on 1000 Boreworms. |
| Killer of Killers (5) | Get an S-rank in Survival Arena mode. |
| Anvil Horror (15) | Get three S-ranks in Survival Arena mode. |
| Jason Schmason (50) | Get six S-ranks in Survival Arena mode. |
| Dead on the Rise (5) | Accomplish 5 Secret Missions in a single Survival Arena attempt. |
| Too much Horror business (10) | Accomplish all 10 Secret Missions in a single Survival Arena attempt. |
| Hunger Pangs (5) | Purchase a skill. |
| Blood Lust (25) | Unlock 25 skills. |
| Lust for After Life (50) | Unlock all skills. |
| Call of the Thule (10) | Unlock 5% of Dr. West's journal. |
| Nightmare in Arkham (20) | Unlock 25% of Dr. West's journal. |
| Lovecraft Baby (20) | Unlock 50% of Dr. West's journal. |
| The House that West Built (100) | Unlock all pages of Dr. West's journal. |
| Jen Smells of Rot…of the Grave (5) | Re-assemble one of Jen's sexy photos. |
| Creepy Show (10) | Re-assemble 8 of Jen's photos. |
| Happy Ending? (20) | Re-assemble all of Jen's photos. |
