| Unlockable | How to unlock |
|---|
| Cat Jumped in My Lap (5) | Die in the spikes in the tutorial area of level 1 |
| Dino's Best Friend (10) | Convert 3 dinosaurs to your side by destroying their helmets |
| Exterminator Sam (10) | Kill a Giant Flea in Fireball Fury |
| Get Some (10) | Buy 16 different upgrades |
| Getting Serious (30) | Beat the campaign on any difficulty |
| Gnaar-body's Fool (10) | Kill over 50 Gnaar in a single level |
| Gun Aficionado (15) | Find all guns |
| GUNSTACKAAAAAAaaahhh! (20) | Create your first 6 gun stack |
| I Heard You Like Parallax (10) | Find the Secret Monument to Parallax |
| Laura Who? (10) | Find All Secrets |
| Like Butta (10) | Trip a Therizinosaurus with the Hot Butter Spreader |
| Monkey's Uncle (10) | Defeat the boss of Ancient Egypt |
| My Man Huff (20) | Beat a level in coop |
| Paradox Shmaradox (10) | Replay any previous level with new inventory (Choose Level menu) |
| Pawn Shop (5) | Revert at least one gun to get some money back |
| Quad Power (10) | Find all 4 of any gun type |
| Red Light Rendezvous (10) | Find the Secret Red Light District |
| Repeat Customer (10) | Buy 4 different upgrades for one gun type |
| Seriously Nuts (15) | Clear 8 Challenge levels |
| Seriously Tough (10) | Clear 2 Challenge levels |
| Seriously Unstoppable (20) | Clear all Challenge levels |
| Speed runner (10) | Complete a level from the start at over 100% gameplay speed in one sitting |
| Templeton's Buddy (10) | Help Templeton unlock his secret room in Amethystine Depths |
| Tickets to the Gun Show (10) | Find 16 guns |
| Tricked Out (20) | Buy at least one of every upgrade |
| Two Can Play At That (20) | Beat a challenge in coop |
| Unflinching Sam (20) | Beat any level without dying |
| Untouchable Sam (20) | Beat any level without getting hurt |
| White Men Can Jump (10) | Find the Jump Pad |
| You Bet Jurassic (20) | Defeat the boss of Prehistoric Nova Scotia |
