Complete each achievement to get the allotted gamerscore. The numbers between the () is the points given for each achievement.
| Achievement | How to unlock |
|---|
| Hunter (10) | Kill 500 enemies. |
| Predator (50) | Kill 1000 enemies. |
| Headache (20) | Kill 200 enemies with headshots. |
| Major League (20) | Land 200 combo throws. |
| Cut a Rug (20) | Land 100 full combo attacks. (3 consecutive hits) |
| Ninja Style (20) | Filena killed 50 enemies. |
| Privacy Issues (10) | Destroy 1 Watcher. (1/50) |
| Stop Looking At Me! (30) | Destroy 20 Watchers. (20/50) |
| Leave Me Alone! (50) | Destroy 50 Watchers. (50/50) |
| Novice (5) | Obtain the rank of Novice. |
| Soldier (10) | Obtain the rank of Soldier. |
| Mercenary (20) | Obtain the rank of Mercenary. |
| Commando (20) | Obtain the rank of Commando. |
| Elite (20) | Obtain the rank of Elite. |
| Slayer (20) | Obtain the rank of Slayer. |
| Berserker (30) | Obtain the rank of Berserker. |
| Storm (30) | Obtain the rank of Storm. |
| Immortal (50) | Obtain the rank of Immortal. |
| Lone Gunman (20) | Kill all members of the opposing team alone. (8-player Team Battle) |
| All Mine (20) | Kill all other players in an 8-player Deathmatch. |
| On a Roll (20) | Kill 10 opponents in a row during one match. |
| Killing Spree (20) | Kill 20 opponents in one match. |
| Triage (20) | Revive 10 teammates in one match. |
| Secret Achievements | - |
| Pierce the Skin (5) | Clear The Root of the Tower. |
| Through the Viscera (5) | Clear Trachea. |
| Xylem (5) | Clear Lumenosynthetic Reactor 2. |
| Fetus (5) | Clear The Womb. |
| Clear Your Mind (5) | Clear Cavitas Cranii. |
| Dermal Lesion (15) | Clear The Root of the Tower on Hard. |
| Internal Trauma (15) | Clear Trachea on Hard. |
| Phloem (15) | Clear Lumenosynthetic Reactor 2 on Hard. |
| Breech (15) | Clear The Womb on Hard. |
| Subdural Hematoma (15) | Clear Cavitas Cranii on Hard. |
| Enlightenment (15) | Clear The Seed of Gnosis. |
| Death & Rebirth (30) | Clear the entire game on Hard. |
| Professional Exterminator (20) | Kill the Gargantua on Hard in 2 minutes 30 seconds or less. |
| Steady, Steady... (20) | Shoot an enemy with a Plasma Lancer from 50m. |
| Five Birds, One Stone (20) | Hit 5 enemies with one shot from the Ifrit. |
| Killing Connoisseur (30) | Kill 10 enemies with every firearm Syd can equip. (Melee kills don't count.) |
| Matador (20) | Kill the Dreadnought on Hard in 2 minutes or less. |
| Fight Fire with Fire (20) | Shoot down 10 projectiles from the Raven. |
| Getting Intimate (20) | Kill 100 enemies with melee attacks using the Bloodcleaver. |
| Gladiator (20) | Kill the Chariot during Thorax on Hard in 1 minute 30 seconds or less. |
| Warrior (20) | Defeat Thanatos on Hard in 1 minute 30 seconds or less. |
| Nevermore (20) | Kill the Raven on Hard in 2 minutes or less. |
| Entropy (20) | Defeat Chaos (Thanatos II) on Hard in 1 minute 30 seconds or less. |
| Trusty Sidearm (30) | Clear the entire story using only the Revenant. |
| Release (20) | Defeat Diablosis Soma (Thanatos III) on Hard in 3 minutes 30 seconds or less. |
| What a Pal (20) | Don't let any teammates who were setting charges go down during the final battle in The Womb. |
| 8 Seconds with Style (20) | Kill all enemies in Trachea without dying. |
