When your oppent use a play maker before on ofence it is almost always a run.
This way is very easy and it will never really backfire on you. You have your defensive line. Take a guy from one side. I usually take the Right End and move him over outside of the Left End. It works either way if you wanna move the Left End. Anyway now if there is no Tight End you can just get right in there and disrupt or sack the QB. Even if there is a Tight End on that side he is way easier to plow over than the lineman that you line up against at the start. The only way this will backfire is if they run the ball to the side that you just left open. Then there is one less guy to make a tackle and the CPU can get more yards or even a touchdown but if you have good DB's and LB's you should be fine.
If you want to save some money re-signing players wait until the off-season and the "Re-Sign Players" comes up on the schedule. During this time, you may edit the players to a different position. This lowers their overall rating while at that position. This allows you to re-sign such players to much, much cheaper deals (like 33¢ tinned meats that have Red Tide disease ... it's so cheap).
You can now move these players back into their original places and their rating will go back to normal. The contracts in the game are ridiculous, so you can use this trick to make more realistic deals (yeah right -IGN eds.) or just sign everyone to the minimum.
Card #220 - Super Bowl XLI: RLA9R7
Card #221 - Super Bowl XLII: WRLUF8
Card #222 - Super Bowl XLIII: NIEV4A
Card #223 - Super Bowl XLIV: M5AB7L
Card #224 - Aloha Stadium: YI8P8U
Card #225 - '58 Colts: B57QLU
Card #226 - '66 Packers: 1PL1FL
Card #227 - '68 Jets: MIE6WO
Card #228 - '70 Browns: CL2TOE
Card #229 - '72 Dolphins: NOEB7U
Card #230 - '74 Steelers: YO0FLA
Card #231 - '76 Raiders: MOA11I
Card #232 - '77 Broncos: C8UM7U
Card #233 - '78 Dolphins: VIU0O7
Card #234 - '80 Raiders: NLAPH3
Card #235 - '81 Chargers: COAGI4
Card #236 - '82 Redskins: WL8BRI
Card #237 - '83 Raiders: H0EW7I
Card #238 - '84 Dolphins: M1AM1E
Card #239 - '85 Bears: QOETO8
Card #240 - '86 Giants: ZI8S2L
Card #241 - '88 49ers: SP2A8H
Card #242 - '90 Eagles: 2L4TRO
Card #243 - '91 Lions: J1ETRI
Card #244 - '92 Cowboys: W9UVI9
Card #245 - '93 Bills: DLA3I7
Card #246 - '94 49ers: DR7EST
Card #247 - '96 Packers: F8LUST
Card #248 - '98 Broncos: FIES95
Card #249 - '99 Rams: S9OUSW
When entering the codes, remember to use all CAPS.
Mistake Free- XL7SP1
Using this Madden Card will make it impossible for you to throw an interception or fumble the ball for an entire half.
Lame Duck- 5LAWO0
This Madden Card will force your opponent to throw nothing but lob passes for a half. This gives the defense more time to react to the ball, and leads to more deflections and interceptions.