Complete the outlined tasks, and earn the Trophies.
| Trophy | How to unlock |
| Asps very dangerous you go first (Bronze) | Complete all Story Mode Levels in Raiders Hub. |
| You betrayed Shiva! (Bronze) | Complete all Story Mode Levels in Temple of Doom Hub. |
| We named the dog Indiana. (Bronze) | Complete all Story Mode Levels in Crusade Hub. |
| I thought that was closer. (Bronze) | Complete all Story Mode Levels in Skull 1 Hub. |
| Grab the snake! (Bronze) | Complete all Story Mode Levels in Skull 2 Hub. |
| Three times it drops! (Bronze) | Complete all Story Mode Levels in Skull 3 Hub. |
| They were archaeologists! (Bronze) | Complete all Treasure Mode Levels in Skull 3 Hub. |
| Wiped clean by the wrath of God. (Bronze) | Edit a Bonus level in the Builder. |
| What are you looking at Daddy-o? (Bronze) | Create a customised character. |
| I taught you self-reliance. (Bronze) | Complete the Builder Tutorial levels. |
| I don’t believe in hocus-pocus. (Silver) | Complete all Treasure Mode Levels in Raiders Hub. |
| He was good, he was very good. (Silver) | Complete all Bonus Levels in Raiders Hub. |
| *I'm* a conceited ape? (Silver) | Complete all Treasure Mode Levels in Temple of Doom Hub. |
| You dare not do that. (Silver) | Complete all Bonus Levels in Temple of Doom Hub. |
| I can almost reach it! (Silver) | Complete all Treasure Mode Levels in Crusade Hub. |
| Our situation has not improved. (Silver) | Complete all Bonus Levels in Crusade Hub. |
| I meant drop dead... Comrade. (Silver) | Complete all Treasure Mode Levels in Skull 1 Hub. |
| What are you, like 80? (Silver) | Complete all Bonus Levels in Skull 1 Hub. |
| We're not grave robbers. (Silver) | Complete all Treasure Mode Levels in Skull 2 Hub. |
| You’re one crazy old man. (Silver) | Complete all Bonus Levels in Skull 2 Hub. |
| Into the space in-between spaces (Silver) | Complete all Bonus Levels in Skull 3 Hub. |
| And I even like the color. (Silver) | Create a validated Builder level. |
| What a vivid imagination. (Silver) | Complete a 'Build Your Own Adventure'. |
| The Holy Grail, Dr. Jones (Platinum) | All trophies unlocked |
| Secret Trophies | - |
| Seeing communists in our soup (Bronze) | Defeat 50 Russians with Mutt. |
| So what are you, a triple agent? (Bronze) | Destroy Indy 3 times with Mac. |
| 'You're a teacher?' 'Part-time'. (Bronze) | Use Scholar access 10 times. |
| I’d cover my ears if I were you (Bronze) | Fire a Bazooka 100 times. |
| A long time to wait (Silver) | Unlock the Grail Knight. |
| You know how to fly, don't you? (Silver) | Complete all plane races. (Single Player Only) |
| Not as easy as it used to be. (Silver) | Complete Hangar 51 in under 5 minutes. |
| Do svidanya, Dr. Jones. (Silver) | Destroy Indy with Spalko. |
| Now you're getting nasty. (Silver) | Unlock all of the enemies in the game. (Single Player Only) |
| Wow! Holy Smoke! Crash landing! (Silver) | Destroy 100 enemy vehicles. |
| Get on, Gramps! (Silver) | Unlock all of the vehicles in the game. (Single Player Only) |
| You choose the wrong friends. (Silver) | Complete all Story Levels in Quick Play modes. (Single Player Only) |
| What are they? Spacemen? (Silver) | Unlock the Interdimensional Being. (Single Player Only) |
| Obtainer of rare antiquities. (Gold) | Find all the Artifacts in the game. (Single Player Only) |
| No defiant last words Dr. Jones? (Gold) | Complete the game to 100% (Single Player Only) |