| Unlockable | How to unlock |
|---|
| Apprentice Egyptologist | Decipher an Egyptian text. |
| Arachnophobia | Rip 10 Juvenile spiders apart. |
| Are You Serious!? | Complete the game in single player on unmodified serious difficulty. |
| Beast Hunter | Complete a Beast Hunt match |
| Berserker | Kill 3 enemies in one sprint with the Sledgehammer. |
| Bone Crusher | Smash 20 Kleers with the Sledgehammer. |
| Bug Hunt | Squash 10 Hatchling spiders. |
| Cardiac Surgeon | Rip out 10 Rocketeer hearts. |
| Chain Explosion | Kill at least 5 headless kamikazes in one explosion. |
| Chiropractor | Break 10 Soldier necks. |
| Circle of death | Kill at least 3 enemies in one spinning Sledgehammer attack. |
| Classic Outfit | Find sam's classic outfit |
| Clay Pigeons | Kill 5 Cave Demons while they're in air. |
| Co-op Beginner | Complete any level in cooperative with at least 2 players. |
| Co-op Master | Complete the campaign in cooperative with at least 2 players. |
| Coin-op Co-op | Complete a Coin-op cooperative game on normal or higher difficulty. |
| Deathmatch Beginner | Complete a deathmatch game with at least 1 frag. |
| Deathmatch Master | Win 10 deathmatch games. |
| Flag Thief | Score a total of 10 points in CTF matches. |
| Get the hell off my ride! | Secure the bird. |
| Gold Rush | Pick up 100 gold coins. |
| Golden Survivor | Earn a gold medal in Survival. |
| Hammer Time | Frag 20 players with the Sledgehammer. |
| Headsman | Decapitate a Khnum. |
| Heavy Weight Champion | Win one My Burden match with at least 3 players. |
| Instant Killer | Make at least 3 kills in one Instant Kill match. |
| Killer Jewelry | Kill an enemy using the Mutilator. |
| Kleer Wrestler | Tear off 10 Kleer heads. |
| Kung-fu Fighter | Perform all possible finishing moves in the game. |
| Last Man Standing | Win one round in Last Man Standing game with at least 4 players. |
| Life Saver | Pick up at least 10 extra life items. |
| Load of Scrap | Rip scrapjack's head off. |
| Look Ma, I won! | Win a versus match. |
| Look, it's a secret | Find at least 50 secrets in single player. |
| Maintenance time | Blow a Major Biomechanoid into pieces. |
| Master Egyptologist | Decipher all Egyptian texts. |
| Mission completed | Power up the Timelock. |
| Old School | Complete the game in single player without manually reloading, aiming or sprinting. |
| Ophthalmologist | Remove 10 Gnaar eyes. |
| Painful Divorce | Kill a Witch-Bride of Achriman. |
| Problem solver | Solve the riddle of the Sphynx. |
| Queen Hatshepsut | Complete The Guardian of Time in single player on serious difficulty without dying or loading. |
| Rodeo Surfer | Use the Mutilator to surf after a Werebull. |
| Scorpion Slayer | Break 5 Arachnoid necks. |
| Serious Beginner | Complete any level in single player. |
| Serious Run | Complete the game in single player in half the estimated time on each level. |
| Serious Sam | Complete the single player campaign. |
| Skewer | Pierce 5 enemies with one Devastator round. |
| Survivor | Earn a medal in Survival. |
| The doorman should wear a suit | Awake the Guardian of Time. |
| Top Secret | Find all secrets in single player. |
| Trick Shot | Kill the kicked enemy while it is still in the air. |
| Up Close and Personal | Gib 20 enemies from close range with a shotgun. |
| Useful Trophy | Kill an enemy with a gib torn from another enemy. |
| Vista | Find the Vista secret. |
| Wall of Bullets | Kill 20 enemies with the Minigun without releasing the trigger. |
| Wanted Dead or Alive | Rescue professor Stein. So to say. |
