Successfully complete the game under the easy difficulty setting with any rank better than F to unlock Jill's costume from the original Resident Evil and Regina's costume from Dino Crisis. To unlock three additional costumes, successfully complete the game under the hard difficulty setting with a rank of A. This will unlock police miniskirt, disco, and biker costumes.
To acquire the Boutique Key, which unlocks the Boutique in Uptown (where all the extra outfits are), complete the game once and wait for the credits to end, then save the "Next Game" file to receive the key.
Combine the Gold Gear from the Clock Goddess Puzzle with the Silver Gear. The Chronos gear is used to activate clock bells. Insert it into the bell mechanism on the third floor of the Clock Tower.
At the Sales Office in Uptown, the password to unlock the door is ADRAVIL.
Successfully complete the game under the hard difficulty setting to unlock Epilogues. Epilogues are a short diary description of each character in the entire Resident Evil series which describes what happened with that specific person after their adventure. Getting better ratings can unlock the other epilogues. There are eight total Epilogues that can be unlocked.
To get Jill's diary, you must collect all the files in order, semi-hard, but its worth it!
Mix each kind of gun powder with the reloading tool to make ammunition.
| Gun Powder |
Ammo |
| A | 15 Hand Gun Bullets |
| B | 7 Shot Gun Shells |
| C | 10 Grenade Gun Bullets |
| AAB | 20 Shot Gun Shells |
| BBA | 60 Hand Gun Bullets |
| CCC | 24 Magnum Bullets |
| AA | 35 Hand Gun Bullets |
| AC | 10 Flame Rounds |
| BB | 18 Shot Gun Shells |
| BC | 10 Acid Rounds |
| CC | 10 Freeze Rounds |
| AAA | 55 Hand Gun Bullets |
| BBB | 30 Shot Gun Shells |
| Standard Grenade Rounds + A | Flame Rounds |
| Standard Grenade Rounds + B | Acid Rounds |
| Standard Grenade Rounds + C | Freeze Rounds |
If you go into the save room before you go to the police station and mix the A and B gunpowder on the shelf to make C and then mix it with the gunpowder A that you got at the warehouse and then combine it with your reloading tool to make grenade flame rounds you will always get the grenade launcher in the S.T.A.R.S. room.
When entering the Police Station and going into the door in the top left corner you will reach a room with zombies. After killing them, enter the next room, which contains the lockers. Once there, go to the other side to find a locker with a light on it. The game will prompt for a code. The code is either "0131", "0513", "4011", or "4312".
To get the combination to the medical locker in the hospital, go to the room next to that room. Check the dead body in the corner to find one of the following combinations: "513", "101", "498", or "517".
Complete the game once on any of the difficulty settings and wait for the credits to end, then save the "Next Game" file to unlock "The Mercenaries" mini-game. Then, start a new game, choose that saved game, then select "The Mercenaries" mode.
Each time Nemesis is defeated, he will drop a special item:
Confrontation Item
| Confrontation
| Item |
| 1 | EAGLE Parts A |
| 2 | EAGLE Parts B |
| 3 | First Aid Spray Box |
| 4 | BENELLI M3S Parts A |
| 5 | BENELLI M3S Parts B |
| 6 | First Aid Spray Box |
| 7 | Unlimited ammunition Pack |
Note: there are about 3 ways to do this because it changes from time to time. This is only one method and it many not work all the time) The object of the Clock Goddess Puzzle is to get the center clock in the Clock Tower to read twelve oclock. Collect the Amber, Crystal and Obsidian gems from the statues and go to the three clocks on the opposite wall. Facing the clocks, place the Amber gem into the Past clock, the Obsidian into the Present clock, and the Crystal into the Future clock. If done correctly, the Present clock will open, revealing a Gold Gear, a Mercenarys Pocketbook (next to the bodies in the corner) and M.T. rounds (in the alcove).
The oil additive needed to start the trolley is located in a locked store room inside the sales office. To unlock it, pick up the flashy remote on a desk to turn on a TV. You will see a commercial about some product from Umbrella Corp. Make note of that product (Safsprin, Adravil, Aquacure, etc.). Go to the nearby computer where Carlos just shot his zombied friend. You will be prompted for a password. Type in the name of the product to unlocked the storeroom.