The insanely addicting Tetris-like game with an interesting twist. The viruses are invading and it's up to Dr. Mario to foil their plans!


Guide your bi-colored capsules down the medicine bottle and zap the viruses by forming lines of four or more of the same color. Kill all the viruses to advance to the next level.


  • Line up the capsules with the same coloured viruses to eradicate them
  • Plan your moves and execute combo clearings to score more points
  • Choose between 3 speed settings, suitable for all skill levels
  • Challenge a friend to split-screen action as you compete to clear your bottle first
Angelluv01 and 33 others own Dr. Mario
DarkPyroYoshi and 1 others played Dr. Mario
Jun 29, 09 4:47am
My mother's favorite, she introduced me to video games so I bring this one into high respect. DrMario64 N64
May 20, 09 9:24am
My mom's favorite game, and one of mine! DrMario64 N64
Insanity Prevails
Nov 08, 08 10:58am

Mario is no stranger to extending his reach into genres outside of his platforming...

Jul 15, 08 1:01pm
added 2 new screenshots
Feb 26, 05 1:06pm
added a cheat
  • Genre: Puzzle Games
  • Perspective(s): Third Person
  • Developer: Nintendo
  • Publisher: Nintendo
  • Released
    North AmericaOct 1, 1990
    EuropeJun 27, 1991
    JapanJul 27, 1990
  • Player Info:
  • Offline Multi-player (2)
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2 want | 34 own | 2 completed
7.0 / 10
View all 2 screenshots